Sufferers With Worst COVID-19 Could Be Greatest Plasma Donors: Research

Newest Prevention & Wellness Information

TUESDAY, Oct. 27, 2020 (HealthDay Information)

Components akin to intercourse, age and severity of the illness might assist establish COVID-19 survivors who’ve excessive ranges of antibodies that may shield towards the illness, a brand new research suggests.

“These have been important affected person traits that not solely predicted the quantity of antibody however the high quality of that antibody,” stated lead creator Sabra Klein, a professor within the Division of Molecular Microbiology and Immunology at Johns Hopkins Bloomberg College of Public Well being in Baltimore.

Particularly, older males who’ve recovered after a hospital keep for COVID-19 could also be good candidates for donating plasma for treating different contaminated sufferers, the research suggests.

Plasma trials are persevering with, however docs are uncertain easy methods to choose COVID-19 survivors who’re almost certainly to have robust antibody responses.

For the research, researchers examined the blood of 126 COVID-19 survivors and located many variations of their antibody ranges and their antibodies’ potential to neutralize SARS-CoV-2. Components linked with stronger antibody responses included being sick sufficient to be hospitalized, being older and being male.

“We all know that the magnitude of antibody responses correlates with illness severity in different infectious ailments, akin to lively tuberculosis,” Klein stated in a Hopkins information launch.

The findings have been not too long ago revealed within the Journal of Medical Investigation.

— Steven Reinberg

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SOURCE: Johns Hopkins Bloomberg College of Public Well being, information launch, Oct. 20, 2020

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